Publications

BMI OrganBank’s work is grounded in peer-reviewed science. The publications below represent research across organ systems that informs and supports the OrganBank platform’s development.

Kidney

  1. Transplantation Direct
    Subnormothermic Oxygenated Machine Perfusion (24h) in DCD Kidney Transplantation
    Abraham N, et al.

  2. Annals of Surgery
    Mitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation

  3. Transplantation Journal
    Renal Extracellular Matrix Scaffolds from Discarded Kidneys Maintain Glomerular Morphometry and Vascular Resilience and Retain Critical Growth Factors

  4. Nature Biomedical Engineering
    Evolving Adeno-Associated Viruses for Gene Transfer to the Kidney via Cross-Species Cycling of Capsid Libraries
    Rosales A, et al. (2025)

  5. American Journal of Transplantation
    24h OrganBank Decreases DGF Compared to LifePort in Porcine 30min DCD Kidney Auto-Transplantation
    Abraham N, et al. (2026)

  6. American Journal of Transplantation
    OrganBank End-to-End Bloodless 20°C Kidney O₂ Perfusion Eliminates DGF Compared to LifePort
    Abraham N, et al. (2026)

Eye

  1. Investigative Ophthalmology & Visual Science
    Portable Ex Vivo Whole Eye Preservation System: Optimization and Validation in a Porcine Model
    Kopparthy V, et al. (2026)

  2. Transplantation
    Ex Vivo Whole Eye Perfusion System
    Adcock T, et al. (2026)


Liver

  1. Frontiers in Medicine
    Two Compartment Evaluation of Liver Grafts During Acellular Room Temperature Machine Perfusion (acRTMP) in a Rat Liver Transplant Model

  2. Clinical and Translational Discovery
    The Effect of Obeticholic Acid on Hepatic Blood Flow in Isolated, Perfused Porcine Liver

  3. International Journal of Transplantation
    Validation of Cardio-Emulation Pump Perfused, Porcine Liver Model: Blood Flow Response to Temperature


Whole Body / Multi-Organ / Systemic Recovery

  1. Nature
    Cellular Recovery After Prolonged Warm Ischemia of the Whole Body

  2. Nature
    Improved Organ Recovery After Oxygen Deprivation

  3. NIH
    Restoring Cell and Organ Function After the Heart Stops

  4. Scientific American
    How Scientists Revived Dead Pigs’ Organs, and What the Feat Means for Transplants

Lung

  1. JTCVS Techniques
    Dual Ex Vivo Lung Perfusion via Pulmonary and Bronchial Arteries in a Porcine Model
    Nakata K, et al. (2025)


Limbs / VCA

  1. Transplantation
    Human Limb Preservation Using Oxygenated Machine Perfusion with Hemoglobin-Based Oxygen Carriers Modulates Hypoxia and Immune Injury Pathways
    Kopparthy V, et al. (2026)

  2. American Journal of Transplantation 
    Perfluorocarbon Nanoemulsions for Simultaneous Delivery of Oxygen and Antioxidants During Machine Perfusion Supported Organ Preservation
    Janjic JM, et al. (2024)


Brain / CNS

  1. Nature
    Restoration of Brain Circulation and Cellular Functions Hours Post-Mortem


Cross-Organ / Technology Development

  1. Reconstructive Transplantation and Regenerative Surgery
    Preservation Technologies in Organ Transplantation
    Cohen E, Copus J, Kopparthy V

  2. Pharmaceutics
    Perfluorocarbon Nanoemulsions for Simultaneous Delivery of Oxygen and Antioxidants During Machine Perfusion Supported Organ Preservation
    Patel, Smith, et al. (2026)

The Evidence Continues

How Does the Science Translates?

From preclinical outcomes to regulatory milestones, see where the platform stands today.
Keeping more paths to transplant open.

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Blood-free perfusate

Proprietary acellular perfusate designed to support metabolically active preservation—enabling oxygen delivery, nutrient support, and management of oxidative stress without the need for donor-matched blood.

Real-time visibility across the journey

Tracks organ status and location during preservation and transport, supporting coordination and assessment across teams.

Portable perfusion. Continuous preservation.

Automated, portable device designed to maintain kidneys in a metabolically active state during preservation and transport.
Operates at room temperature without donor-matched blood.