The Science of Organ Preservation

Preserving an organ is about more than maintaining time. It is about maintaining function.

The Challenge Begins at Recovery

Once an organ is recovered, biological processes immediately begin to change. Preservation science seeks to protect organ health between donation and transplant.

Science Note 01: Ischemia →

Maintaining Cellular Function

Cells require oxygen and nutrients to support normal biological activity. Preserving function outside the body requires carefully managing these metabolic demands.

Science Note 02: Reperfusion Injury →

Balancing Temperature and Metabolism

Temperature influences metabolism, energy use, and tissue stress. Preservation strategies use temperature to help manage these biological processes.

Science Note 03: Organ Metabolism →

Supporting Flow Outside the Body

Organs evolved within a circulatory system. Preservation technologies can support flow while providing opportunities to observe physiologic conditions.

Science Note 04: Perfusion Science →

From Preservation to Assessment

Time alone does not fully describe organ health. Modern preservation science increasingly focuses on generating meaningful information before transplantation.

Science Note 05: Understanding viability assessment →

The Future of Preservation

Researchers continue exploring new approaches to preservation, assessment, and transplantation. The goal remains simple: helping more donated organs and tissues reach the patients who need them.

Expanding What Preservation Makes Possible

BMI OrganBank is developing technologies designed to support metabolically active preservation, physiologic visibility, and operational continuity within a connected preservation environment.

Keeping more paths to transplant open.

PLATFORM & TECHNOLOGY

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Blood-free perfusate

Proprietary acellular perfusate designed to support metabolically active preservation—enabling oxygen delivery, nutrient support, and management of oxidative stress without the need for donor-matched blood.

Real-time visibility across the journey

Tracks organ status and location during preservation and transport, supporting coordination and assessment across teams.

Portable perfusion. Continuous preservation.

Automated, portable device designed to maintain kidneys in a metabolically active state during preservation and transport.
Operates at room temperature without donor-matched blood.